Cardiac Allograft Vasculopathy in Adult Congenital Heart Disease Patients Requiring Cardiac Transplantation
نویسندگان
چکیده
منابع مشابه
Prevention of Cardiac Allograft Vasculopathy in Heart Transplantation
Heart transplantation is a well established therapy for end-stage heart failure. Long-term results are limited by malignancy and cardiac allograft vasculopathy. The causes for cardiac allograft vasculopathy and the predictors for its onset and progression are multifactorial and determined by both immunological and non-immunological risk factors. The detection of cardiac allograft vasculopathy i...
متن کاملCONGENITAL HEART DISEASE Changing practice of cardiac surgery in adult patients with congenital heart disease
Objectives: To review 13 years’ data from a unit for grown ups with congenital heart disease (GUCH) to understand the change in surgical practice. Methods: Records were reviewed of patients over 16 years of age undergoing surgery between 1 January 1990 and 31 December 2002 in a dedicated GUCH unit. Patients with atrial septal defects were included but not those with Marfan’s syndrome or undergo...
متن کاملCardiac allograft vasculopathy in Dutch heart transplant recipients
BACKGROUND Cardiac allograft vasculopathy (CAV) is a multifactorial disease and a major cause of graft failure after heart transplantation. However, the impact of CAV may vary according to the definition and the regional differences in transplantation settings. OBJECTIVES We sought to assess CAV prevalence, predictors and prognosis in Dutch heart transplant recipients based on coronary angiog...
متن کاملCardiac allograft vasculopathy: recent developments.
Cardiac allograft vasculopathy (CAV) continues to limit the long-term success of cardiac transplantation. Recent insights have underscored the fact that innate and adaptive immune responses are involved in the pathogenesis of CAV. Vascular lesions are the result of cumulative endothelial injuries induced both by alloimmune responses and by nonspecific insults (including ischemia-reperfusion inj...
متن کاملCardiac allograft vasculopathy: a review.
Cardiac allograft vasculopathy (CAV) is a major factor limiting long-term survival after cardiac transplantation. CAV is an accelerated form of coronary artery disease (CAD) that is characterized by concentric fibrous intimal hyperplasia along the length of coronary vessels. Both immunologic and nonimmunologic risk factors contribute to the development of CAV by causing endothelial dysfunction ...
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ژورنال
عنوان ژورنال: The Journal of Heart and Lung Transplantation
سال: 2021
ISSN: 1053-2498
DOI: 10.1016/j.healun.2021.01.595